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Free base   Listen
noun
Free base  n.  
1.
(Chem.) The basic form of an organic amine which is capable of forming acid salts such as hydrochlorides.
2.
The basic form of a drug, often more powerful than a salt form because it is more readily absorbed into the blood stream.





Collaborative International Dictionary of English 0.48


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"Free base" Quotes from Famous Books



... has been isolated by M. Lobry de Bruyn, and a preliminary account of its mode of preparation and properties is published by him in the current number of the Recueil des travaux chimiques des Pays-Bas (1891, 10, 101). The manner in which the free base was obtained was briefly as follows. About a hundred grammes of hydroxylamine hydrochloride, NH{2}OH.HCl, were dissolved in six hundred cubic centimeters of warm methyl alcohol. To this solution a quantity of sodium dissolved in methyl alcohol was added, in such proportion that ...
— Scientific American Supplement, No. 841, February 13, 1892 • Various
... The free base is liberated by adding to the phenylhydrazine hydrochloride 1 l. of a 25 per cent solution of sodium hydroxide. The phenylhydrazine separates and is taken up with benzene (two 300-cc. portions). The combined extractions are well dried with 200 g. of solid sodium hydroxide, poured off, and distilled. ...
— Organic Syntheses • James Bryant Conant


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