SYSTEMIC • DICCIONARIO INGLES.COM • Definition of Systemic

... that this is not a virus trouble, but a systemic defect, probably caused by chromosome aberration or gene abnormality. It is significant that this trouble occurs only in hybrids. Such trees never flower. We have known four such cases, two of which are now dead. Similar types appear ...

— Northern Nut Growers Association Report of the Proceedings at the 43rd Annual Meeting - Rockport, Indiana, August 25, 26 and 27, 1952 • Various

... never develop any serious infection or display very high resisting power in the later stages, others, again, will stand forty slight inoculations with absolute impunity, and yet, when once the leucocyte-barrier is broken down, will make apparently little resistance to a fatal systemic infection. And this, of course, is only one of a score of ways in which the leucocytes literally pro patria moriuntur. Our whole alimentary canal is continually patrolled by their squadrons, poured into it by the tonsils above and Peyer's patches ...

— Preventable Diseases • Woods Hutchinson